iGEM Thessaly 2019: Odyssee


A modular platform for instant diagnosis of Tuberculosis. Tuberculosis (TB) is one of the 10 deadliest diseases worldwide, causing around 1.3 million deaths in 2017 and nearly 3 million people are left undiagnosed, each year. Once Mycobacterium tuberculosis, which causes the disease, dies in a patient’s lung, it releases DNA fragments into the blood that eventually appear in urine. We developed a diagnostic test that detects these fragments by targeting the specific gene IS6110. After 4 rounds of amplification including isothermal amplification, in vitro transcription/translation of a toehold switch and a colorimetric readout enabled by b-lactamase, the results can be visualized with a naked eye. Our design can be easily implemented for several diseases due to its universality and modularity. As TB is a leading health threat for populations affected by crises, our test is destined to be applied in refugee camps in Greece, as well as worldwide, making a step towards achieving universal health coverage.

You can learn more about Odyssee 2019 here

Odyssee's 2019 Poster


Swipe to meet the team

Vasiliki Kavvatha
Project Leader

Leandros Tsiotos
Project Leader

Afroditi Katsaouni
Wet Lab

Niokoleta Efthymiopoulou
Wet Lab

Nikolaos Ntelkis
Wet Lab

Thodoris Kontogiannis
Wet Lab

Xenia - Artemis Doulka

Eleftheria Moustaka
Wiki Design

Maria Gerontopoulou
Graphic Design

Athina Milona
Human Practices

Our medals

Gold Medal

Diagnostic 2019

Nominee Best Integrated
Human Practices 2019

Nominee Best Supporting
Entrepreneurship 2019