The forced population movements due to the humanitarian crisis (war, sexual abuse, inequality) that has prevailed for years in their countries of origin is a problem of global dimensions that plagues modern society. Since 2015, nearly one million people have crossed Turkey's coasts, mainly from West Asian countries, and have reached a Greek island, seeking shelter in northern Europe.

According to the UN High Commissioner for Refugees, refugees displaced due to war or persecution are often in a very vulnerable position. As the density of people arriving at the first reception points is increased, they are deprived of fundamental human rights, including access to healthcare. This can easily lead to the outbreak of illnesses for which the provision of health services is incomplete. One of these illnesses is tuberculosis.

According to the World Health Organization's annual report, tuberculosis is one of the 10 deadliest diseases worldwide, causing around 1.3 million deaths in 2017. At the same time, 10 million people are estimated to be infected by tuberculosis in 2017.

Tuberculosis is caused by the pathogenic bacterium Mycobacterium tuberculosis and mainly affects the respiratory system and in particular the lungs. When the defense system of the organism cannot stop its development, M. tuberculosis becomes active. Thus, active mycobacteria multiply within the body and cause the disease. When people who carry the mycobacterium are coughing or sneezing, the disease can be transmitted through the air.

All patients with tuberculosis are entitled to access to innovative tools and services for rapid diagnosis, treatment, and care. It is a matter of social justice and a significant goal for the achievement of global health coverage.

Utilizing the principles of Synthetic Biology, we recommend the development of a rapid, reliable and safe test for early diagnosis of tuberculosis without the need for specialized personnel and equipment for its execution. We aim to replace conventional diagnostics by providing a new tool for people working in health structures. As a result of our work, we hope for more effective care for people in refugee shelters in our country.

iGEM Thessaly 2019